Isaac S Kohane Selected Research

1- (4- hydroxy- 3- methoxyphenyl)- 7- (3,4- dihydroxyphenyl)- 4E- en- 3- heptanone

5/2009

Cytotoxic diarylheptanoid induces cell cycle arrest and apoptosis via increasing ATF3 and stabilizing p53 in SH-SY5Y cells.

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Isaac S Kohane Research Topics

Disease

13	Neoplasms (Cancer) 09/2021 - 03/2002
4	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 10/2007 - 11/2002
3	COVID-19 12/2021 - 01/2021
3	Breast Neoplasms (Breast Cancer) 11/2021 - 05/2004
3	Inflammation (Inflammations) 01/2021 - 07/2006
3	Medulloblastoma 02/2015 - 01/2009
3	Nemaline Myopathies (Nemaline Myopathy) 10/2007 - 04/2003
2	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 06/2019
2	Acoustic Neuroma (Acoustic Neurinoma) 11/2018 - 01/2018
2	Major Depressive Disorder (Major Depressive Disorders) 10/2012 - 01/2012
2	Brain Neoplasms (Brain Tumor) 01/2011 - 01/2009
2	Myocardial Infarction 03/2010 - 09/2007
2	Type 2 Diabetes Mellitus (MODY) 12/2009 - 06/2007
2	Insulin Resistance 12/2009 - 06/2007
2	Fibrosis (Cirrhosis) 07/2006 - 04/2003
1	Rheumatoid Arthritis 11/2021
1	Genetic Risk Score 11/2021
1	Infections 10/2021
1	Autism Spectrum Disorder 01/2021
1	Anxiety Disorders (Anxiety Disorder) 01/2021
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2021
1	Adenocarcinoma 01/2020
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Carcinoma (Carcinomatosis) 01/2020
1	Hypothyroidism 01/2020
1	Autistic Disorder (Autism) 01/2020
1	Dyslipidemias (Dyslipidemia) 01/2020
1	Undiagnosed Diseases 11/2018
1	Hyperlipidemias (Hyperlipidemia) 10/2018
1	Neurilemmoma (Schwannoma) 01/2018
1	Schizophrenia (Dementia Praecox) 01/2018
1	Meningioma (Meningiomas) 01/2018
1	Premature Birth (Birth, Premature) 11/2017
1	Prostatic Neoplasms (Prostate Cancer) 02/2016
1	Obesity 01/2016
1	Intellectual Disability (Idiocy) 01/2015
1	Wounds and Injuries (Trauma) 10/2014
1	Weight Gain 08/2014
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2014
1	Cardiomyopathies (Cardiomyopathy) 03/2014
1	Cardiac Arrhythmias (Arrythmia) 01/2013
1	Hemorrhage 01/2012
1	Stroke (Strokes) 01/2012
1	Huntington Disease (Huntington's Disease) 07/2011

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 01/2020 - 11/2002
6	Biological ProductsIBA 11/2018 - 03/2004
4	Messenger RNA (mRNA)IBA 01/2015 - 03/2002
3	Immune Checkpoint InhibitorsIBA 09/2021 - 06/2019
3	RNA (Ribonucleic Acid)IBA 01/2020 - 11/2002
3	MicroRNAs (MicroRNA)IBA 02/2015 - 10/2007
3	Antidepressive Agents (Antidepressants)IBA 08/2014 - 01/2012
3	DystrophinIBA 10/2005 - 11/2002
3	Complementary DNA (cDNA)IBA 04/2005 - 03/2002
3	OligonucleotidesIBA 07/2004 - 03/2002
2	VaccinesIBA 12/2021 - 10/2021
2	ProcalcitoninIBA 10/2021 - 01/2021
2	C-Reactive ProteinIBA 10/2021 - 01/2021
2	Mifepristone (RU 486)FDA Link 11/2018 - 01/2018
2	Pharmaceutical PreparationsIBA 01/2018 - 06/2007
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 02/2015 - 01/2011
2	Citalopram FDA LinkGeneric 08/2014 - 01/2013
2	DNA (Deoxyribonucleic Acid)IBA 03/2014 - 03/2002
2	EnzymesIBA 10/2007 - 04/2003
1	BNT162 VaccineIBA 12/2021
1	mRNA VaccinesIBA 12/2021
1	Eosine Yellowish-(YS) (Eosin)IBA 11/2021
1	Hematoxylin (Haematoxylon)IBA 11/2021
1	Biomarkers (Surrogate Marker)IBA 11/2021
1	CreatinineIBA 10/2021
1	Fibrinogen (Factor I)FDA Link 10/2021
1	fibrin fragment D (D-dimer)IBA 10/2021
1	Ferritins (Ferritin)IBA 10/2021
1	Antipsychotic Agents (Antipsychotics)IBA 01/2021
1	ApoferritinsIBA 01/2021
1	Complement System Proteins (Complement)IBA 01/2021
1	pembrolizumabIBA 01/2020
1	NivolumabIBA 01/2020
1	PlatinumIBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2019
1	oxidized low density lipoproteinIBA 10/2018
1	LDL CholesterolIBA 10/2018
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 01/2018
1	Progesterone FDA LinkGeneric 01/2018
1	17 alpha-Hydroxyprogesterone Caproate (Delalutin)FDA Link 11/2017
1	antiarrhythmic peptide (AAP)IBA 01/2016
1	Amitriptyline (Elavil)FDA LinkGeneric 08/2014
1	Bupropion (Wellbutrin)FDA LinkGeneric 08/2014
1	Nortriptyline (Aventyl)FDA LinkGeneric 08/2014
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2013
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 10/2012
1	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2012
1	polyglutamineIBA 07/2011
1	Metformin (Glucophage)FDA LinkGeneric 03/2010

Therapy/Procedure

4	Therapeutics 01/2021 - 05/2009
3	Drug Therapy (Chemotherapy) 01/2020 - 05/2009
2	Immunotherapy 09/2021 - 01/2020
1	Precision Medicine 01/2020
1	Aftercare (After-Treatment) 01/2020
1	Patient Readmission 10/2014
1	Genomic Medicine 03/2014